With Pittsburgh snarled by a New Year's Eve blizzard and Angels of Mercy Hospital cut off from the outside world, staff and patients are at the mercy of armed gunmen. Their target is Dr. Gina Freeman, who is holding vigil over her wounded fiancé, Detective Jerry Boyle. Trapped inside with her are ER charge nurse Nora Halloran and fourth-year medical student Amanda Mason, on the last night of her ICU rotation, and possibly her life. Stranded outside the hospital walls is ER physician Lydia Fiore, whose past holds the secret the hitmen are willing to kill for. With patients, staff, and loved ones held hostage, the power out, and cold-blooded killers in control, who will live to see the New Year?

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